Immunohistochemical detection of p53 and PCNA in ameloblastoma and adenomatoid odontogenic tumor
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چکیده
منابع مشابه
Immunohistochemical detection of p53 and PCNA in ameloblastoma and adenomatoid odontogenic tumor.
Although ameloblastoma and adenomatoid odontogenic tumor (AOT) belong to the same group according to the World Health Organization, they show different biologic behaviors. PCNA, an amplifier of cell proliferation, and p53, a tumor suppressor protein, are overexpressed in some odontogenic lesions. The purpose of this study was to immunohistochemically evaluate the expression of p53 and PCNA to c...
متن کاملProliferating cell nuclear antigen (PCNA) and p53 protein expression in ameloblastoma and adenomatoid odontogenic tumor.
In this study, proliferating cell nuclear antigen (PCNA) and p53 protein expressions were analyzed in 16 cases of ameloblastoma and 8 cases of adenomatoid odontogenic tumor (AOT). The cases of ameloblastoma consisted of solid type tumors and histologic arrangements of different subtypes were observed. In some specimens, more than one histologic subtype was identified in the same lesion, and eac...
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OBJECTIVES Since its recognition as a physiologic process associated with tumor, among molecular mechanisms involved in tumor progression, defects in regulation of apoptosis have generated an accelerating volume of research that has sought to elucidate the role of programed cell death in pathogenesis and treatment of various tumors. Therefore, this study was performed to understand better the d...
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Adenomatoid odontogenic tumor (AOT) is an uncommon benign odontogenic lesion that affects young patients, with female predominance, mainly in second decade, showing a radiolucent unilocular image associated with an unerupted tooth, usually a canine. In spite of previous and confusing denominations, such as adenoameloblastoma or adenomatoid ameloblastic tumor, AOT is a benign tumor with a very l...
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Adenomatoid odontogenic tumor is an uncommon benign Hamartomatous lesion of odontogenic origin, which affects young individuals, with female predilection and mainly occurring in second decade of life. Maxillary anterior region is most often involved, and associated with unerupted or impacted canine. We report a rare case of treated multilocular adenomatoid odontogenic tumor of posterior mandibl...
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ژورنال
عنوان ژورنال: Journal of Oral Science
سال: 2011
ISSN: 1880-4926,1343-4934
DOI: 10.2334/josnusd.53.213